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HE BODY Background About this chapter The benzodiazepines Potency Speed of elimination Duration of effects Therapeutic actions of benzodiazepines Mechanisms of action Adverse effects of benzodiazepines Oversedation Drug interactions Memory impairment Paradoxical stimulant effects Depression, emotional blunting Adverse effects in the elderly Adverse effects in pregnancy Tolerance Dependence Therapeutic dose dependence Prescribed high dose dependence Recreational benzodiazepine abuse Socioeconomic costs of long-term benzodiazepine use Further reading Table 1. Benzodiazepines and similar drugs Table 2. Therapeutic actions of benzodiazepines Table 3. Some socioeconomic costs of long-term benzodiazepine use Fig. 1. Diagram of mechanism of action of the natural neurotransmitter GABA (gamma aminobutyric acid) and benzodiazepine on nerve cells (neurons) in the brain CHAPTER II. HOW TO WITHDRAW FROM BENZODIAZEPINES AFTER LONG-TERM USE Background Why should you come off benzodiazepines? Before s valium withdrawal


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Tarting benzodiazepine withdrawal Consult your doctor and pharmacist Make sure you have adequate psychological support Get into the right frame of mind Be confident Be patient Choose your own way The withdrawal Dosage tapering Switching to a long-acting benzodiazepine Designing and following the withdrawal schedule Withdrawal in older people Withdrawal of antidepressants Further reading Slow withdrawal schedules 1. Withdrawal from high dose (6mg) alprazolam (Xanax) daily with diazepam (Valium) substitution 2. Simple withdrawal from diazepam (Valium) 40mg daily 3. Withdrawal from lorazepam (Ativan) 6mg daily with diazepam (Valium) substitution 4. Withdrawal from nitrazepam (Mogadon) 10mg at night with diazepam (Valium) substitution 5. Withdrawal from clonazepam (Klonopin) 1.5mg daily with substitution of diazepam (Valium) 6. Withdrawal from clonazepam (Klonopin) 3mg daily with substitution of diazepam (Valium) 7. Withdrawal from alprazolam (Xanax) 4mg daily with diazepam (Valium) substi

valium withdrawal symptoms G-term use & 149; Chapter II: Slow withdrawal schedules & 149; Chapter III: Benzodiazepine withdrawal symptoms valium withdrawal symptoms, acute & protracted CONTENTS PAGE FOREWORD 2001 FOREWORD TO REVISED EDITION valium withdrawal symptoms, AUGUST 2002 ABOUT PROFESSOR C HEATHER ASHTON valium withdrawal symptoms, DM valium withdrawal symptoms, FRCP SUMMARY OF CONTENTS MEDICAL DISCLAIMER CHAPTER I. THE BENZODIAZEPINES: WHAT THEY DO IN THE BODY Background About this chapter The benzodiazepines Potency Speed of elimination Duration of effects Therapeutic actions of benzodiazepines Mechanisms of action Adverse effects of benzodiazepines Oversedation Drug interactions Memory impairment Paradoxical stimulant effects Depression valium withdrawal symptoms, emotional blunting Adverse effects in the valium withdrawal symptoms.

valium withdrawal symptoms Elderly Adverse effects in pregnancy Tolerance Dependence Therapeutic dose dependence Prescribed high dose dependence Recreational benzodiazepine abuse Socioeconomic costs of long-term benzodiazepine use Further reading Table 1. Benzodiazepines and similar drugs Table 2. Therapeutic actions of benzodiazepines Table 3. Some socioeconomic costs of long-term benzodiazepine use Fig. 1. Diagram of mechanism of action of the natural neurotransmitter GABA (gamma aminobutyric acid) and benzodiazepine on nerve cells (neurons) in the brain CHAPTER II. HOW TO WITHDRAW FROM BENZODIAZEPINES AFTER LONG-TERM USE Background Why should you come off benzodiazepines? Before starting benzodiazepine withdrawal Consult your doctor and pharmacist Make sure you have adequate psychological support Get into the right frame of mind Be confident Be patient Choose your own way The withdrawal Dosage tapering Switching to a long-acting benzodiazepine Designing and following the withdrawal schedule Withdrawal in older people Withdrawal of antidepressants Further reading Slow withdrawal schedules 1. Withdrawal from high dose (6mg) alprazolam (Xanax) daily with diazepam (Valium) substitution 2. Simple withdrawal from diazepam (Valium) 40mg daily 3. Withdrawal from lorazepam (Ativan) 6mg daily with diazepam (Valium) substitution 4. Withdrawal fro.

valium withdrawal symptoms Rting benzodiazepine withdrawal Consult your doctor and pharmacist Make sure you have adequate psychological support Get into the right frame of mind Be confident Be patient Choose your own way The withdrawal Dosage tapering Switching to a long-acting benzodiazepine Designing and following the withdrawal schedule Withdrawal in older people Withdrawal of antidepressants Further reading Slow withdrawal schedules 1. Withdrawal from high dose (6mg) alprazolam (Xanax) daily with diazepam (Valium) substitution 2. Simple withdrawal from diazepam (Valium) 40mg daily 3. Withdrawal from lorazepam (Ativan) 6mg daily with diazepam (Valium) substitution 4. Withdrawal from.

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valium withdrawal symptoms Rs,' admits Suzanne, now 22. 'I'm sad I missed out on so much with Chloe. I want to make it up to her and Mum. I definitely won't go back on tranquillisers. The past few years have been like a terrible dream but I can see a future now.' Dr Alan Nye, who helped Suzanne withdraw, says: 'Long-term prescription of tranquillisers shouldn't happen at any age. They're only useful if the patient's having a short-term crisis. It was hard for Suzanne, but with the help of her wonderful mum, she did it.' Tranquillisers in the UK - The Facts... Around one million people are addicted to tranquillisers in the UK. In a poll carried out by the NOP Research Group, 28 per cent of those on tranquillisers said they'd been on them for more than 10 years. In 1988 the government's Committee on the Safety of Medicines recommended to GPs that benzodiazepine tranquillisers (including temazepam, diazepam and lorazepam) should not be prescribed for more than four weeks. After that, patients can become dependent.

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