Metformin hydrochloride. Glucophage (metformin hydrochloride). Alpharma inc. - court extends temporary restraining order on ....

metformin hydrochloride LUCOPHAGEÒ XR (metformin hydrochloride extended-release tablets) are oral antihyperglycemic drugs used in the management of type 2 diabetes. Metformin hydrochloride (N metformin hydrochloride, N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Metformin hydrochloride is a white to off-white crystalline compound with a molecular formula of C4H11N5 . HCl and a molecular weight of 165.63. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone metformin hydrochloride, ether metformin hydrochloride, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochl metformin hydrochloride.

metformin hydrochloride Oride is 6.68. Its structural formula is: GLUCOPHAGE tablets contain 500 mg metformin hydrochloride, 850 mg metformin hydrochloride, or 1000 mg of metformin hydrochloride. Each tablet contains the inactive ingredients povidone and magnesium stearate. In addition metformin hydrochloride, the coating for the 500 mg and 850 mg tablets contains hydroxypropyl methylcellulose (hypromellose) and the coating for the 1000 mg tablet contains hydroxypropyl methylcellulose and polyethylene glycol. GLUCOPHAGE XR contains 500 mg or 750 mg of metformin hydrochloride as the active ingredient. GLUCOPHAGE XR 500 mg tablets contain the inactive ingredients sodium carboxymethyl cellulose metformin hydrochloride, hydroxypropyl methylcellulose metformin hydrochloride, microcrystalline cellulose metformin hydrochloride, and magnesium stearate. GLUCOPHAGE XR 750 mg tablets contain the inactive ingredients sodium carboxymethyl cellulose metformin hydrochloride, hydroxypropyl methylcellulose metformin hydrochloride, and magnesium stearate. System Components and Performance - GLUCOPHAGE XR comprises a dual hydrophilic polymer matrix system. Metformin hydrochloride is combined with a drug release controlling polymer to form an "inner" phase metformin hydrochloride, which is then incorporated as discrete particles into an "external" phase of a second polymer. After administration metformin hydrochloride, fluid from the gastrointestinal (GI) tract enters the tablet metformin hydrochloride, causing the polymers to hydrate and swell. Drug is released slowly from the dosage form by a process of diffusio.

metformin hydrochloride D magnesium stearate. GLUCOPHAGE XR 750 mg tablets contain the inactive ingredients sodium carboxymethyl cellulose metformin hydrochloride, hydroxypropyl methylcellulose metformin hydrochloride, and magnesium stearate. System Components and Performance - GLUCOPHAGE XR comprises a dual hydrophilic polymer matrix system. Metformin hydrochloride is combined with a drug release controlling polymer to form an "inner" phase metformin hydrochloride, which is then incorporated as discrete particles into an "external" phase of a second polymer. After administration metformin hydrochloride, fluid from the gastrointestinal (GI) tract enters the tablet metformin hydrochloride, causing the polymers to hydrate and swell. Drug is released slowly from the dosage form by a process of diffusion.

metformin hydrochloride