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mg tramadol hydrochloride tramadol Cyclopedia Jump to: navigation, search Tramadol Systematic (IUPAC) name rac-(1R,2R)-2-(dimethylaminomethyl)-1- (3-methoxyphenyl)-cyclohexanol Identifiers CAS number 27203-92-5 ATC code N02AX02 PubChem 33741 DrugBank APRD00028 Chemical data Formula C16H25NO2& 160; Mol. weight 263.4 g mol Pharmacokinetic data Bioavailability 68-72% Increases with repeated dosing. Protein binding 20% Metabolism Hepatic demethylated & glucuronidated Half life 5-7 hours Excretion Renal Therapeutic considerations Pregnancy cat. C(AU) C(US) Legal status Prescription Only (S4)(AU) POM(UK) Routes oral, IV, IM Tramadol (INN) (IPA: ˈtræməˌdɒl ) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. It is a synthetic agent, unrelated to other opioids, and appears to have actions on the GABAergic, noradrenergic and serotonergic systems. Tramadol was developed by the German pharmaceutical company Grünenthal GmbH and marketed under the trade name Tramal. Grü