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S. Some people develop a need to continue taking their medicines. This is known as dependence or "addiction." When people develop dependence, they may have difficulty stopping the sleep medicine. If the medicine is suddenly stopped, the body is not able to function normally and unpleasant symptoms (see Withdrawal) may occur. They may find they have to keep taking the medicine either at the prescribed dose or at increasing doses just to avoid withdrawal symptoms. All people taking sleep medicines have some risk of becoming dependent on the medicine. However, people who have been dependent on alcohol or other drugs in the past may have a higher chance of becoming addicted to sleep medicines. This possibility must be considered before using these medicines for more than a few weeks. If you have been addicted to alcohol or drugs in the past, it is important to tell your doctor before starting zolpidem tartrate or any sleep medicine. Withdrawal: Withdrawal symptoms may occur when
zolpidem tartrate . Special Concerns There are some special problems that may occur while taking sleep medicines. Memory Problems: Sleep medicines may cause a special type of memory loss or "amnesia." When this occurs zolpidem tartrate, a person may not remember what has happened for several hours after taking this medicine. This is usually not a problem since most people fall asleep after taking the medicine. Memory loss can be a problem zolpidem tartrate, however zolpidem tartrate, when sleep medicines are taken while traveling zolpidem tartrate, such as during an airplane flight and the person wakes up before the effect of the medicine is gone. This has been called "traveler's amnesia." Memory problems are not common while zolpidem tartrate.
zolpidem tartrate Taking zolpidem tartrate. In most instances memory problems can be avoided if you take zolpidem tartrate only when you are able to get a full night's sleep (7 to 8 hours) before you need to be active again. Be sure to talk to your doctor if you think that you are having memory problems. Tolerance: When sleep medicines are used every night for more than a few weeks zolpidem tartrate, they may lose their effectiveness to help you sleep. This is known as "tolerance." Sleep medicines should zolpidem tartrate, in most cases zolpidem tartrate, be used only for short periods of time zolpidem tartrate, such as 1 or 2 days and generally no longer than 1 or 2 weeks. If your sleep problems continue zolpidem tartrate, consult your doctor zolpidem tartrate, who will determine whether other measures are needed to overcome your sleep problems. Dependence: Sleep medicines can cause dependence zolpidem tartrate, especially when these medicines are used zolpidem tartrate, regularly for longer than a few weeks or at high doses. Some people develop a need to continue taking their medicines. This is known as dependence or "addiction." When people develop dependence zolpidem tartrate, they may have difficulty stopping the sleep medicine. If the medicine is suddenly stopped zolpidem tartrate, the body is not able to function normally and unpleasant symptoms (see Withdrawal) may occur. They may find they have to keep taking the medicine either at the prescribed dose or at increasing doses jus.
zolpidem tartrate Etermine whether other measures are needed to overcome your sleep problems. Dependence: Sleep medicines can cause dependence zolpidem tartrate, especially when these medicines are used zolpidem tartrate, regularly for longer than a few weeks or at high doses. Some people develop a need to continue taking their medicines. This is known as dependence or "addiction." When people develop dependence zolpidem tartrate, they may have difficulty stopping the sleep medicine. If the medicine is suddenly stopped zolpidem tartrate, the body is not able to function normally and unpleasant symptoms (see Withdrawal) may occur. They may find they have to keep taking the medicine either at the prescribed dose or at increasing doses just.
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Pidem to healthy volunteers was 59 nanograms per mL (nanograms mL) (0.077 micromoles per L micromoles L ), with a range of 29 to 113 nanograms mL (0.038 to 0.148 micromoles L); C m a x following administration of 10 mg of zolpidem was 121 nanograms mL (0.158 micromoles L) with a range of 58 to 272 nanograms mL (0.076 to 0.356 micromoles L) . Elimination: Renal & 151; 48 to 67% of a single dose is eliminated in the urine . Unchanged zolpidem is present in trace amounts in urine and feces . Fecal & 151; 29 to 42% of a single dose is eliminated in the feces . Unchanged zolpidem is present in trace amounts in urine and feces . In dialysis& 151; Not hemodialyzable . Precautions to Consider Carcinogenicity Tumorigenicity No evidence of carcinogenic potential was observed in mice administered zolpidem in doses of 4, 18, and 80 mg per kg of body weight (mg kg) per day (26 to 520 times the recommended human dose of 10 mg per day on a mg kg basis) for 2 years . In rats administered zolpidem in d
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