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Yridine have not been performed in the pediatric population. However, no pediatrics-specific problems have been documented to date. Geriatrics Although appropriate studies with phenazopyridine have not been performed in the geriatric population, no geriatrics-specific problems have been documented to date. However, elderly patients are more likely to have age-related renal function impairment, which may increase the risk of accumulation and toxicity in patients receiving phenazopyridine. Laboratory value alterations The following have been selected on the basis of their potential clinical significance (possible effect in parentheses where appropriate)& 151;not necessarily inclusive (& 187; = major clinical significance): With physiology laboratory test values Urinalyses based on color reaction or spectroscopy , for example: Bilirubin, urine, determined via foam test, talc-disk& 150;Fouchetspot test, or Franklin"s tablet-Fouchet test methods Glucose, urine, determined using glucose oxid phenazopyridine hydrochloride


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Ase 17-Hydroxycorticosteroids, urine, determined via Glenn-Nelson method Ketones, urine, determined using sodium nitroprusside or Gerhardt ferric chloride test 17-Ketosteroids, urine, determined via Haltorff Koch modification of Zimmerman reaction Kidney function tested via phenolsulfonphthalein (PSP) excretion Protein, urine, determined using bromophenol blue test reagent strips or nitric acid ring test Urobilinogen, urine, determined using Ehrlich"s reagent (phenazopyridine may interfere with test results by causing discoloration of the urine ) Medical considerations Contraindications The medical considerations contraindications included have been selected on the basis of their potential clinical significance (reasons given in parentheses where appropriate)& 151; not necessarily inclusive (& 187; = major clinical significance). Except under special circumstances, this medication should not be used when the following medical problem exists: Renal function impairment (increased risk of

phenazopyridine hydrochloride of impaired fertility. Pregnancy& 151; Adequate and well-controlled studies have not been done in humans. Studies in rats with doses up to 50 mg kg per day have not shown evidence of harm to the fetus. FDA Pregnancy Category B. Breast-feeding It is not known whether phenazopyridine or any of its metabolites are distributed into breast milk. However phenazopyridine hydrochloride, problems in humans have not been documented. Pediatrics Appropriate studies with phenazopyridine have not been performed in the pediatric population. However phenazopyridine hydrochloride, no pediatrics-specific problems have been documented to date. Geriatrics Although appropriate studies with phenazopyridine have not been performed in the phenazopyridine hydrochloride.

phenazopyridine hydrochloride Geriatric population phenazopyridine hydrochloride, no geriatrics-specific problems have been documented to date. However phenazopyridine hydrochloride, elderly patients are more likely to have age-related renal function impairment phenazopyridine hydrochloride, which may increase the risk of accumulation and toxicity in patients receiving phenazopyridine. Laboratory value alterations The following have been selected on the basis of their potential clinical significance (possible effect in parentheses where appropriate)& 151;not necessarily inclusive (& 187; = major clinical significance): With physiology laboratory test values Urinalyses based on color reaction or spectroscopy phenazopyridine hydrochloride, for example: Bilirubin phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined via foam test phenazopyridine hydrochloride, talc-disk& 150;Fouchetspot test phenazopyridine hydrochloride, or Franklin"s tablet-Fouchet test methods Glucose phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using glucose oxidase 17-Hydroxycorticosteroids phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined via Glenn-Nelson method Ketones phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using sodium nitroprusside or Gerhardt ferric chloride test 17-Ketosteroids phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined via Haltorff Koch modification of Zimmerman reaction Kidney function tested via phenolsulfonphthalein (PSP) excretion Protein phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using bromophenol blue test reagent strips or nitric acid ring test Urobilinogen phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using Ehrlich"s reagent (phenazopyridine may interfere with test results by causing discoloration of the urine ) Medi.

phenazopyridine hydrochloride 150;Fouchetspot test phenazopyridine hydrochloride, or Franklin"s tablet-Fouchet test methods Glucose phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using glucose oxidase 17-Hydroxycorticosteroids phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined via Glenn-Nelson method Ketones phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using sodium nitroprusside or Gerhardt ferric chloride test 17-Ketosteroids phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined via Haltorff Koch modification of Zimmerman reaction Kidney function tested via phenolsulfonphthalein (PSP) excretion Protein phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using bromophenol blue test reagent strips or nitric acid ring test Urobilinogen phenazopyridine hydrochloride, urine phenazopyridine hydrochloride, determined using Ehrlich"s reagent (phenazopyridine may interfere with test results by causing discoloration of the urine ) Medic.

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phenazopyridine hydrochloride Ic situation treatment may include gastric lavage and activated charcoal administration, methylene blue administration, and blood transfusion in severe refractory cases.4 Renal failure can occur as a complication of phenazopyridine-related methemoglobinemia and hemolytic anemia. As previously mentioned, phenazopyridine hydrochloride is contraindicated in clients with impaired renal and hepatic function. For this reason use of this agent in the elderly is very limited. The agent should not be used in clients with a creatinine clearance less than 50 ml min.5 All clients taking this medication should be instructed to observe for a yellow appearance of the skin and sclera. This may indicate an accumulation of the drug owing to renal impairment AND A NEED TO DISCONTINUE THERAPY. If discoloration occurs, the drug should be immediately discontinued and the prescriber immediately notified. Color changes in skin or sclera can also indicate hepatotoxicity. It is alarming that phenazopyridine-ind

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