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Total expenses 220,453 181,939 150,598 552,990 ---------- ---------- ---------- --------- Net loss $(138,784) $(70,490) $(21,368) $(230,642) ========== ========== ========== ========= 2003 --------------------------------------------------- Q1 Q2 Q3 Q4 TOTAL ---------- --------- --------- --------- ---------- Revenue: Product sales, net: United States $- $- $- $27,922 $27,922 Europe 16,615 21,853 26,154 30,442 95,064 Canada and Mexico - - 2,295 4,547 6,842 --------------------------------------------------- 16,615 21,853 28,449 62,911 129,828 Royalties 975 3,115 4,352 6,263 14,705 ---------- --------- --------- --------- ---------- Total revenue 17,590 24,968 32,801 69,174 144,533 ---------- --------- --------- --------- ---------- Expenses: Cost of sales 1,604 2,170 2,803 5,966 12,543 Selling, general and administrative 42,396 48,544 49,145 103,025 243,110 Research and development 16,685 14,344 14,735 17,858 63,622 ---------- --------- --------- --------- ---------- Total expenses 60,