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Ution and in reduced dosages when administered to patients receiving CNS depressants such as alcohol, opioids, anesthetic agents, narcotics, phenothiazines, tranquilizers or sedative hypnotics. Tramadol increases the risk of CNS and respiratory depression in these patients. Increased Intracranial Pressure or Head Trauma ULTRACET should be used with caution in patients with increased intracranial pressure or head injury. The respiratory depressant effects of opioids include carbon dioxide retention and secondary elevation of cerebrospinal fluid pressure and may be markedly exaggerated in these patients. Additionally, pupillary changes (miosis) from tramadol may obscure the existence, extent, or course of intracranial pathology. Clinicians should also maintain a high index of suspicion for adverse drug reaction when evaluating altered mental status in these patients if they are receiving ULTRACET (see Respiratory Depression). Use in Ambulatory Patients Tramadol may impair the mental and tramadol dosage


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Or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. The patient using this drug should be cautioned accordingly. Use With MAO Inhibitors and Serotonin Re-uptake Inhibitors Use ULTRACET with great caution in patients taking monoamine oxidase inhibitors. Animal studies have shown increased deaths with combined administration of MAO inhibitors and tramadol. Concomitant use of tramadol with MAO inhibitors or SSRI’s increases the risk of adverse events, including seizure and serotonin syndrome. Use With Alcohol ULTRACET should not be used concomitantly with alcohol consumption. The use of ULTRACET in patients with liver disease is not recommended. Use With Other Acetaminophen-containing Products Due to the potential for acetaminophen hepatotoxicity at doses higher than the recommended dose, ULTRACET should not be used concomitantly with other acetaminophen-containing products. Withdrawal Withdrawal symptoms may occu

tramadol dosage Ol may obscure the existence tramadol dosage, extent tramadol dosage, or course of intracranial pathology. Clinicians should also maintain a high index of suspicion for adverse drug reaction when evaluating altered mental status in these patients if they are receiving ULTRACET (see Respiratory Depression). Use in Ambulatory Patients Tramadol may impair the mental and or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. The patient using this drug should be cautioned accordingly. Use With MAO Inhibitors and Serotonin Re-uptake Inhibitors Use ULTRACET with great caution in patients taking monoamine oxidase inhibitors. tramadol dosage.

tramadol dosage Animal studies have shown increased deaths with combined administration of MAO inhibitors and tramadol. Concomitant use of tramadol with MAO inhibitors or SSRI’s increases the risk of adverse events tramadol dosage, including seizure and serotonin syndrome. Use With Alcohol ULTRACET should not be used concomitantly with alcohol consumption. The use of ULTRACET in patients with liver disease is not recommended. Use With Other Acetaminophen-containing Products Due to the potential for acetaminophen hepatotoxicity at doses higher than the recommended dose tramadol dosage, ULTRACET should not be used concomitantly with other acetaminophen-containing products. Withdrawal Withdrawal symptoms may occur if ULTRACET is discontinued abruptly. (See DRUG ABUSE AND DEPENDENCE.) These symptoms may include: anxiety tramadol dosage, sweating tramadol dosage, insomnia tramadol dosage, rigors tramadol dosage, pain tramadol dosage, nausea tramadol dosage, tremors tramadol dosage, diarrhea tramadol dosage, upper respiratory symptoms tramadol dosage, piloerection tramadol dosage, and rarely hallucinations. Other symptoms that have been seen less frequently with ULTRACET discontinuation include: panic attacks tramadol dosage, severe anxiety tramadol dosage, and paresthesias. Clinical experience suggests that withdrawal symptoms may be avoided by tapering ULTRACET at the time of discontinuation. Physical Dependence and Abuse Tramadol may induce psychic and physical dependence of the morphine-type (& 181;-opioid). (See DRUG ABUSE AND DEPENDENCE.) Tramado.

tramadol dosage occur if ULTRACET is discontinued abruptly. (See DRUG ABUSE AND DEPENDENCE.) These symptoms may include: anxiety tramadol dosage, sweating tramadol dosage, insomnia tramadol dosage, rigors tramadol dosage, pain tramadol dosage, nausea tramadol dosage, tremors tramadol dosage, diarrhea tramadol dosage, upper respiratory symptoms tramadol dosage, piloerection tramadol dosage, and rarely hallucinations. Other symptoms that have been seen less frequently with ULTRACET discontinuation include: panic attacks tramadol dosage, severe anxiety tramadol dosage, and paresthesias. Clinical experience suggests that withdrawal symptoms may be avoided by tapering ULTRACET at the time of discontinuation. Physical Dependence and Abuse Tramadol may induce psychic and physical dependence of the morphine-type (& 181;-opioid). (See DRUG ABUSE AND DEPENDENCE.) Tramadol.

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tramadol dosage N on drug safety and efficacy. Tramal long was used mainly for severe and very severe pain. The most frequently reported causes of pain were diseases of the locomotor system (49.9%), tumours (24.3%), traumas and fractures (10.1%), and neurogenic (9.3%). The mean daily dose was 235.7 mg, usually divided into two doses. The analgesic effect was described as very good or good by 82.5% of the patients. Adverse events occurred in 6.5% of the patients, mostly in the form of typical opioid side-effects such as nausea (3.4%), dizziness (1.5%) and vomiting (1.1%). Severe or unknown side-effects were not reported. Morphine Tramadol Immune response Tramadol: metabolites Tramadol and analgesia Tramadol and acute pain Tramadol versus morphine Tramadol versus oxycodone Official prescribing indications Tramadol as an antidepressant Tramadol: risk benefit analysis Tramadol versus buprenorphine Pharmacokinetics and pharmacodynamics Tramadol, depression and Parkinson's disease Monoamine function: tramad

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